Warmth/ Hyperthermia

Psychotropic medications can increase body temperature: e.g. modafinil, a xanthosine analogue PMID 12433231. Meditation can also increase body temperature without exogenous compounds 23555572

Most commonly ignored in psychiatry, except in cases of malignant catatonia (acute g deficit, often via PNP inhibition?)/ NMS/ serotonin syndrome (Inosine or inosine analogue excess).

Paroxetine increases perceived body temperature, an effect most commonly felt as chills in withdrawal, but demonstrates real decrease in body temperature in paroxetine withdrawal from overdose 11169163.

Body temperature increases significantly during the latter half of the menstrual cycle: temperature dysregulation in menopause (hot flashes) are actual fluctuations in body temperature, and are reduced by paroxetine PMID 24601805.

Some SPMI patients, especially those taking mild PNP-activator clozapine, have difficulty maintaining warmth, wear multiple layers of clothing.